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Fox purchased the series, though the network’s then-president, Gail Berman, advised the creative staff, “I need a medical present, but I don’t want to see white coats taking place the hallway”. Jacobs has said that this stipulation was one of the many influences that led to the show’s ultimate kind. House was among the many high 10 collection within the United States from its second via fourth seasons. Distributed to 71 nations, it was the most-watched TV program in the world in 2008.

The primary patient within the pilot episode is called Rebecca Adler after Irene Adler, a character in the first Holmes short story, “A Scandal in Bohemia”. In the season two finale, House is shot by a crazed gunman credited as “Moriarty”, the name of Holmes’s nemesis. In the season 4 House & Home Improvement news episode “It’s a Wonderful Lie”, House receives a “second-edition Conan Doyle” as a Christmas present. In the season five episode “The Itch”, House is seen choosing up his keys and Vicodin from the highest of a replica of Conan Doyle’s The Memoirs of Sherlock Holmes.